Quantitative Whole-Body MRI
In his Editorial “Advancing Cancer Care with Modern MRI” Professor Padhani points out that many aspects of cancer care remain on ‘red alert’ as we enter the second decade of the 21st century. There are many times when healthcare professionals cannot confidently answer questions that directly affect patient care. Seemingly simple questions such as “Do I have cancer?”, “Is the cancer going to kill me?”, “Is my cancer responding to therapy?”, “Is the cancer back?” and “How long do I have to live?”, “Will I make it to my daughter’s wedding?” evade us on a daily basis. While we struggle to respond to the needs of our patients, we remain aware that progress is being made every day in cancer diagnosis and therapy, and within this, is the role being played by MRI as highlighted by articles and videos on this page.
Application Tips & Protocols
Whole-Body MRI at 1.5T in the Era of Deep Resolve.
Step-by-step video tutorial with MAGNETOM Sola and software version syngo MR XA51
Will McGuire, Deputy MRI Superintendent Radiographer (Paul Strickland Scanner Centre, Northwood, Middlesex, UK)
The "Comprehensive" protocol includes a fast FLAIR brain scan, lung imaging and additional VIBE sequences. This protocol will be the more widely compatible version as it does not include Deep Resolve or other advanced acceleration techniques.
The "Core" protocol is typically used for bone-only disease. This protocol contains Deep Resolve Gain and Deep Resolve Sharp enhanced sequences.
You can mix and match sequences from both protocols to best suit your requirements.
Deep Resolve Boost enhanced protocols will be uploaded when syngo MR XA60/61 becomes widely available.
Whole-Body MRI at 1.5T in the Era of Deep Resolve
Will McGuire; Marie Fennessy; Anwar R. Padhani
(Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK)
Whole-body MRI at 1.5T: step-by-step video tutorial
with MAGNETOM Avantofit and software version syngo MR E11C
Will McGuire, Deputy Superintendent Radiographer, Paul Strickland Scanner Centre, Northwood, Middlesex, UK
Whole-body MRI has been used as a clinical tool at Paul Strickland Scanner Centre for over 10 years. In that time they have performed over 6,500 examinations, using a protocol designed to enable the detection and surveillance of metastatic bone and soft tissue disease. Will McGuire, Linda Culver and Anwar R. Padhani share their .exar1 protocol file exported from a MAGNETOM Avantofit running software version syngo MR E11C.
Whole-body MRI protocols from The Royal Marsden Hospital
Radiology Department at The Royal Marsden, London, UK
The department of Diagnostic Radiology at the Royal Marsden Hospital, one of the leading institutions in advanced oncological imaging and specializing in functional and whole-body MR imaging in the assessment of lesion biology and therapy response, shares clinically optimized and proven protocols for whole-body MRI on different 1.5T MAGNETOM systems.
- Download MAGNETOM Sola 1.5T WB-MRI protocols (.exar1 files and PDFs) (7z) 0.72 MB
- Download MAGNETOM Aera 1.5T WB-MRI protocols (.exar1 files and PDFs) (7z) 0.69 MB
- Download MAGNETOM Avanto 1.5T WB-MRI protocols (.edx file and PDFs) (zip) 0.18 MB
- Accompanying notes for whole-body MRI protocols (pdf) 0.1 MB
Whole-body MRI at 1.5T: step-by-step
Will McGuire, Deputy Superintendent Radiographer, Paul Strickland Scanner Centre, Northwood, Middlesex, UK
Pediatric Whole-Body MRI: How I Do It
Bac Nguyen, BSc; Lil-Sofie Muller, M.D., Ph.D., Oslo University Hospital, Rikshospitalet, Oslo, Norway
How-I-do-it: Whole-body MRI including DWI
David Hillier, MR Application Specialist, Siemens Healthineers Great Britain and Ireland
Whole-Body Dot Engine: First Clinical Experience with Automated Chest, Abdomen and Pelvis Examinations
Caecilia S. Reiner, M.D., Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland
Frequently Asked Questions: Diffusion-Weighted Imaging
Joachim Graessner, Dipl. Ing., Siemens Healthineers, Hamburg, Germany
Clinical Talks and Articles
Initial Experiences Using Deep Resolve Boost to Accelerate Whole-Body Diffusion MRI
Andrea Ponsiglione, PhD (University of Naples Federico II, Naples, Italy); Anwar R. Padhani, MB, BS, FRCP, FRCR; et al.
(Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood, UK)
MR Total Tumor Load – First Clinical Experience in Pediatric Oncology Patients
Ilias Tsiflikas, Jürgen F. Schäfer; University Hospital Tübingen, Germany
Developing Whole-body MRI for Precision Oncology
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Whole-body MR diffusion imaging in oncology: origins, practice, and outlook
Giuseppe Petralia, M.D., et al., European Institute of Oncology, Milan, Italy
Progress on whole-body MRI use for advanced breast cancer
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Watching Cancer Develop Multidrug Resistance
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Quantitative WB-MRI with ADC Histogram Analysis for Response Assessment in Diffuse Bone Disease
Danoob Dalili, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Quantitative WB-MRI with ADC Histogram Analysis for Complex Response of Bone Marrow Metastatic Disease
Danoob Dalili, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Evolution of the Malignant Bone Marrow with Successful Therapy – Quantitative Analysis with Whole-body Diffusion-weighted MRI
Danoob Dalili, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Priya V. Joshi, Mount Vernon Cancer Centre and the East and North Herts NHS trust hospitals, Northwood, Middlesex, UK
Whole-body Diffusion-weighted MRI: The Time has Come for a Change
Atul Kapoor, Goldaa Mahajan, Aprajita Kapoor, Department of Radiology and Magnetic Resonance Imaging, Advanced Diagnostics Amritsar, Punjab, India
Observing Endocrine Therapy Resistance in Metastatic Breast Cancer with Whole-body MRI
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Metastatic Prostate Cancer in Practice The MET-RADS-P Imaging Response System Using Whole-body MRI
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Nina Tunariu, Royal Marsden NHS Foundation Trust & Institute of Cancer Research and Cancer Research UK Cancer Imaging Centre, Sutton, Surrey, UK
Monitoring Bone Marrow Metastases Treatment with Whole-Body Diffusion MRI
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Whole Body Diffusion-Weighted MRI for Bone Marrow Tumor Detection
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
Initial Experience with Whole-Body Diffusion-Weighted Imaging in Oncological and Non-Oncological Patients
Leonardo Kayat Bittencourt, Clínica de Diagnóstico por Imagem, Rio de Janeiro, Brazil
Whole-Body Diffusion-Weighted MRI of the Bone Marrow in Health and Disease
Anwar R. Padhani, Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK
18F-FDG PET/MR: Its Incremental Value in Assessing the Multiple Myeloma Patient
Shetal N. Shah, M.D., Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA
Hybrid PET/MR Imaging with PSMA-Ligands: The Future Standard in the Diagnosis of Prostate Cancer?
Ali Afshar-Oromieh, M.D., Department of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany
![Siemens - MRI - MAGNETOM World - Hot Topics - Quantitative Whole-Body MRI - Combining [18F] PET with MR for Detection of Bone Metastases in One Simultaneous Examination - Lentschig](https://marketing.webassets.siemens-healthineers.com/1800000004386179/4d8c88c5cb5b/v/b17b9af8c6bd/Combining_18F_PET_with_MR_for_Detection_Bone_Metastases_NWD_1800000004386179.jpg)
Combining [18F] PET with MR for Detection of Bone Metastases in One Simultaneous Examination
Markus Lentschig, CEMODI, Centre for Modern Diagnostics, Bremen, Germany
Product News
Whole-body Diffusion-weighted MR Image Analysis with syngo.via Frontier MR Total Tumor Load
Robert Grimm, Siemens Healthineers, Erlangen, Germany
Whole-body MR Image Reading and Bone Assessment with syngo.via Frontier MR Bone Scan
Matthias Fenchel, Siemens Healthineers, Erlangen, Germany