MAGNETOM Cima.X User Community
MAGNETOM Cima.X makes the difference for clinical and research users. With its high-performance Gemini Gradients operating with a maximum amplitude of 200 mT/m (±3% for design tolerances) at a slew rate of 200 T/m/s, it bridges the realm of high-end research with the clinical arena.
The MAGNETOM Cima.X user community serves as a central hub for knowledge, protocols, and best practices exchange. We encourage everyone of our users to contribute to foster a vital lively community.
Image Gallery
MAGNETOM Cima.X is a full-blown clinical scanner, delivering the image quality you can expect from Siemens Healthineers. Please find here examples from users working with MAGNETOM Cima.X in clinical routine.
Scientific presentations
Advancing Diffusion MRI for Comprehensive Characterisation of the Prostate Gland
Malwina Molendowska, Ph.D. (CUBRIC, Cardiff, UK / Lund University, Sweden)
In her talk at ESMRMB 2023 Dr. Molendowska explains why high gradient amplitudes make a difference for research and potential clinical translation.
Scientific literature
Stay up to date on the latest progress leveraging the benefits of strong gradients. Be it in basic research, translational or clinical, here is a repository of relevant publications to get you started.
Peer-reviewed papers
Benefits of high gradient strength
Molendowska M, Mueller L, Fasano F, Jones DK, Tax CMW, Engel M. Giving the prostate the boost it needs: Spiral diffusion MRI using a high-performance whole-body gradient system for high b-values at short echo times. Magn Reson Med.
2025;93(3):1256–1272.
Genc S, Ball G, Chamberland M, Raven EP, Tax CMW, … Jones DK, et al. MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression. Nat Commun. 2025;16(1):3317.
Kara D, Liu Y, Chen S, Garrett T, Younis A,… Nguyen C, et al. In vivo cardiac diffusion tensor imaging on an MR system featuring ultrahigh performance gradients with 200 mT/m maximum gradient strength. Magn Reson Med. 2025;93(2):673–688.
Afzali M, Mueller L, Coveney S, Fasano F, Evans CJ, Engel M, et al. In vivo diffusion MRI of the human heart using a 300 mT/m gradient system. Magn Reson Med. 2024;92(3):1022–1034.
Engel M, Mueller L, Döring A, Afzali M, Jones DK. Maximizing SNR per unit time in diffusion MRI with multiband T-Hex spirals. Magn Reson Med. 2024;91(4):1323–1336.
Molendowska M, Palombo M, Foley KG, Narahari K, Fasano F, Jones DK, et al. Diffusion MRI in prostate cancer with ultra-strong whole-body gradients. NMR Biomed. 2024;37(12):e5229.
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/nbm.5229
Genc S, Schiavi S, Chamberland M, Tax CMW, Raven EP, Daducci A, Jones DK. Developmental differences in canonical cortical networks: Insights from microstructure-informed tractography. Netw Neurosci. 2024;8(3):946–964.
https://direct.mit.edu/netn/article/8/3/946/120696/Developmental-differences-in-canonical-cortical
Afzali M, Mueller L, Coveney S, Fasano F, Evans CJ,… Schneider JE, et al. In vivo diffusion MRI of the human heart using a 300 mT/m gradient system. Magn Reson Med. 2024;92(3):1022–1034.
Genc S, Raven EP, Drakesmith M, Blakemore SJ, Jones DK. Novel insights into axon diameter and myelin content in late childhood and adolescence. Cereb Cortex. 2023;33(10):6435–6448.
Tax CMW, Genc S, MacIver CL, Nilsson M, Wardle M, Szczepankiewicz F, et al. Ultra-strong diffusion-weighted MRI reveals cerebellar grey matter abnormalities in movement disorders. Neuroimage Clin. 2023;38:103419.
Raven EP, Veraart J, Kievit RA, Genc S, Ward IL, Hall J, et al. In vivo evidence of microstructural hypo-connectivity of brain white matter in 22q11.2 deletion syndrome. Mol Psychiatry. 2023;28(10):4342–4352.
Endt S, Engel M, Naldi E, Assereto R, Molendowska M, Mueller L, et al. In Vivo Myelin Water Quantification Using Diffusion-Relaxation Correlation MRI: A Comparison of 1D and 2D Methods. Appl Magn Reson. 2023;54(11-12):1571–1588.
https://link.springer.com/article/10.1007/s00723-023-01584-1
Jones DK, Alexander DC, Bowtell R, Cercignani M, Dell'Acqua F, McHugh DJ, et al. Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI. Neuroimage. 2018;182:8-38.
Huang SY, Nummenmaa A, Witzel T, Duval T, Cohen-Adad J, Wald LL, et al. The impact of gradient strength on in vivo diffusion MRI estimates of axon diameter. Neuroimage. 2015;106:464–72.
Huang SY, Tobyne SM, Nummenmaa A, Witzel T, Wald LL, McNab JA, et al. Characterization of Axonal Disease in Patients with Multiple Sclerosis Using High-Gradient-Diffusion MR Imaging. Radiology. 2016;280(1):244–51.
Clinical papers
Bischoff LM, Endler C, Krausewitz P, Ellinger J, Klümper N, Isaak A, et al. Ultra-high gradient performance 3-Tesla MRI for super-fast and high-quality prostate imaging: initial experience. Insights Imaging. 2024;15(1):287.
Kara D, Liu Y, Chen S, Garrett T, Younis A, Sugawara M, et al. In vivo cardiac diffusion tensor imaging on an MR system featuring ultrahigh performance gradients with 200 mT/m maximum gradient strength. Magn Reson Med. 2024.
MAGNETOM Flash
Malwina Molendowska; et al. MRI of the Prostate: The Promise of Ultra-Strong Gradients and Advanced Microstructural Imaging MAGNETOM Flash. 2025;91(2):2–13.
Fischer A, Liu W, Zhou K. Optimizing EPI Image Quality Beyond Linear Phase Corrections with Dual-Polarity GRAPPA. MAGNETOM Flash. 2023;84(2):26–31.
Kimmlingen, R. Pioneers of Connectome Gradients. MAGNETOM Flash. 2017;68(2):122–136.
Protocol exchange
Make the most out of your MAGNETOM Cima.X by sharing protocols with your peers. We encourage the community to contribute and submit their own protocols. Please reach out to us:
magnetomworld.team@siemens-healthineers.com