Diffusion MRI can play an essential role in better understanding the pathophysiology of MS and in monitoring the disease course and, possibly, response to treatments. Here we provide examples of the research applications and the potential clinical impact of this technique that has not been fully exploited to date. The use of multishell sequences coupled with advanced microstructural models and quantitative tractography might really help to investigate multiple sclerosis pathophysiology and monitor structural connectivity changes.
Advanced Diffusion MRI in Neurological Diseases: The Multiple Sclerosis Model
Matilde Inglese, MD, PhD, et al. (University of Genoa, Italy)
MRI Techniques in Multiple Sclerosis: New Diagnostic and Research Developments
Contact
Professor Matilde Inglese, M.D., Ph.D.
University of Genoa, DINOGMI
Largo Paolo Daneo 3
16134, Genoa
Italy
m.inglese@unige.it